St. Louis Cardinals at Arizona Diamondbacks odds, picks and predictions (2024)

The Arizona Diamondbacks (6-8) welcome the St. Louis Cardinals (7-7) for the 2nd of their 3-game series Saturday. First pitch from Chase Field is set for 8:10 p.m. ET. Let’s analyzeFanDuel Sportsbook’slines around the Cubs vs. Diamondbacks odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 1-0

The Cardinals kicked off the series with a 9-6 win Friday, closing at +108 on the moneyline. St. Louis has lost 3 of its last 5 games and is 4-4 straight up on the road. The Cardinals are 10-4 against the spread (ATS) this season. They sit 5th in the National League Central.

The Diamondbacks came into this series having won 2 of 3 against the Colorado Rockies. They are just 2-6 over their last 8 games. Arizona is 4-4 straight up at home this season. It sits 3rd in the National League West.

Cardinals at Diamondbacks projected starters

RHP Kyle Gibson vs. RHP Ryne Nelson

Gibson (1-1, 6.23 ERA) makes his 3rd start. He has a 1.08 WHIP, 2.1 BB/9 and 6.2 K/9 through 13 IP.

• Last start: Loss, 6 IP, 7 ER, 7 H, 1 BB, 5 K in a 10-3 home loss to the Miami Marlins Sunday
• 2023 road splits: 9-4, 4.57 ERA (112 1/3 IP, 57 ER — 13 HR), 31 BB, 89 K in 19 starts

Nelson (0-2, 8.22 ERA) makes his 3rd start. He has a 1.83 WHIP, 4.7 BB/9 and 10.6 K/9 through 7 2/3 IP.

• Last start: Loss, 5 IP, 3 ER, 5 H, 0 BB, 7 K in a 5-2 road loss to the Atlanta Braves Sunday
• 2023 home splits: 6-3, 3.46 ERA (88 1/3 IP, 34 ER — 12 HR), 23 BB, 65 K in 15 starts (16 appearances)

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Cardinals at Diamondbacks odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:05 p.m. ET.

• Moneyline (ML): Cardinals -108 (bet $108 to win $100) | Diamondbacks -108 (bet $108 to win $100)
• Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+140) | Diamondbacks +1.5 (-170)
• Over/Under (O/U): 10 (O: -110 | U: -110)

Cardinals at Diamondbacks picks and predictions

Prediction

Diamondbacks 5, Cardinals 4

Moneyline

BET DIAMONDBACKS (-108).

The Cardinals are just 2-4 straight up following a win, which they are here. St. Louis has lost the game following its last 2 wins. Gibson wasn’t great on the road last season and is coming off an ugly performance Sunday.

Nelson was solid at home a year ago, and the Diamondbacks have won 2 of their last 3 games, closing as a favorite in each. Arizona was 46-42 straight up at home a season ago as well.

Considering the trends here, back DIAMONDBACKS (-108).

Run line/Against the spread

PASS.

There’s no good value on the run line as the Cardinals are too expensive and have covered too consistently this season to bet against. The Diamondbacks are far too expensive as a run-line underdog.

Over/Under

LEAN UNDER 10 (-110).

The Diamondbacks are 8-6 O/U, but they have gone Under in 3 of their last 5 games. They have also gone Under in both games which Nelson has started on the mound.

The Cardinals are 5-7-2 O/U this season and have gone Under in 3 of their last 4 and in 4 of their last 6. St. Louis has scored 3 or fewer in 5 of its last 6 games, so it hasn’t had an overly dynamic offense either.

That said, back UNDER 10 (-110).

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